2007年8月畢業(yè)于華中科技大學(xué)同濟(jì)醫(yī)學(xué)院，畢業(yè)后一直在浙江大學(xué)醫(yī)學(xué)院附屬婦產(chǎn)科醫(yī)院從事婦產(chǎn)科的臨床及科研工作。2007年獲婦產(chǎn)科博士學(xué)位，2015-2017年赴美國(guó)國(guó)立衛(wèi)生研究院/國(guó)家轉(zhuǎn)化科學(xué)促進(jìn)中心（NIH/NCATS）學(xué)習(xí)，主要從事卵巢癌藥物篩選方面的研究。目前任浙江省醫(yī)學(xué)會(huì)婦科腫瘤學(xué)分會(huì)青年委員兼秘書(shū)。已發(fā)表論文近10篇，主持國(guó)家自然科學(xué)基金2項(xiàng)。
發(fā)表的主要論著：
[1] Sima N, Cheng X, Ye F, Ma D, Xie X, Lu W. The Overexpression of Scaffolding Protein NEDD9 Promotes Migration and Invasion in Cervical Cancer via Tyrosine Phosphorylated FAK and SRC. PLoS One 2013; 8(9): e74594.
[2] Sima N, Lu W, Xie X. Early proteins E6 and E7 of human papillomavirus may attenuate ischemia-reperfusion injury. Med Hypotheses 2011; 76(4): 607-9.
[3] Sima N, Wang W, Kong D, Deng D, Xu Q, Zhou J, Xu G, Meng L, Lu Y, Wang S, Ma D. RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulation of Rb and p53. Apoptosis 2008; 13(2): 273-81.
[4] Sima N, Wang S, Wang W, Kong D, Xu Q, Tian X, Luo A, Zhou J, Xu G, Meng L, Lu Y, Ma D. Antisense targeting human papillomavirus type 16 E6 and E7 genes contributes to apoptosis and senescence in SiHa cervical carcinoma cells. Gynecol Oncol 2007; 106(2): 299-304.
[5] Sima N, Cai L, Zhu Y, Wang W, Wang S, Ma D. Relationship between the expression of telomerase and human papillomavirus infection in invasive uterine cervical carcinoma. J Huazhong Univ Sci Technolog Med Sci 2007; 27(4): 451-3.
[6] Wang W, Sima N, Kong D, Luo A, Gao Q, Liao S, Li W, Han L, Wang J, Wang S, Lu Y, Wang D, Xu G, Zhou J, Meng L, Ma D. Selective targeting of HPV-16 E6/E7 in cervical cancer cells with a potent oncolytic adenovirus and its enhanced effect with radiotherapy in vitro and vivo. Cancer Lett 2010; 291(1): 67-75.
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